VERMILLION, a city of South Dakota, U.S.A., and the seat of the State university. Pop. 193o Federal census, 2,85o. A trading post was established here soon after the first steamboat came up the Missouri river in 1832, and numerous settlers came before the public land was thrown open in 1859. The city was incorporated in 1877. A monument marks the site of the first school building
erected in the State. The university was established (and located in Vermillion) by the first Territorial Legislature of Dakota in 1862, but was not opened until 1882. The enrolment in 1926-27 was 1,375.