BROWNLEE, JOHN (1868-1927), Scottish medical statis tician. After holding various medical appointments, in 1914 he became statistician to the medical research committee. His best known works include the memoir on the epidemiology of phthisis, and his investigations of the laws governing the rise and decline of epidemic diseases, especially measles and influenza. He died on March 20, 1927.
CHARLES EDWARD (1817 1894), British physiologist and neurologist, was born at Port Louis, Mauritius, on April 8, 1817 of mixed American-French parentage. After graduating in medicine at Paris in 1846 he held chairs at Harvard university and at Paris. Eventually he suc ceeded Claude Bernard in 1878 as professor of experimental medi cine in the College de France. He died on April 2, 1894 at Sceaux. Brown-Sequard was the first scientist to work out the physiology of the spinal cord, demonstrating that the decussation of the sensory fibres is in the cord itself. He also did valuable work on the internal secretion of organs, the results of which have been applied with the most satisfactory results in the treatment of myxoedema. Unfortunately, in his extreme old age, he advocated the hypodermic injection of a fluid prepared from the testicles of sheep as a means of prolonging human life. It was known among scientists, derisively, as the Brown-Sequard elixir. His researches, published in about soo essays and papers, especially in the Archives de Physiologie, which he helped to found in 1868, cover a very wide range of physiological and pathological subjects.