ANALGEN. — Analgen is a derivative of quinoline and occurs as a white crys talline powder readily soluble in hot alco hol, slightly so in cold alcohol, but in soluble in water. It is tasteless.
Dose.—The dose is from 4 to 10 grains, repeated every three hours if necessary.
Maximum single dose 15 grains and the maximum daily dose 1 drachm. Schreiber (Amer. Medico-Surg.
Jan. 25, '05).
Although of no pathological signifi cance, the fact that analgen causes a red discoloration of the urine sometimes frightens the patient, and he should be informed of this phenomenon.
Physiological Action.—Analgen seems to act upon the sensitive centres, lower ing their excitability. The separation products of the drug are frequently elim inated by the urine, which is of a red color, rendered more marked by the ad dition of acetic acid,-1 to 10 (Dujardin Beaumetz and Dubief). Bicarbonate of
soda, given internally, is said to prevent this discoloration.
Therapeutics.—Analgen is mainly used in the treatment of conditions in which pain is a prominent feature.
NE LIRALGIA.—In this disorder it often proves very efficient.
Antineuralgic action tested in 22 cases. In 10 of simple neuralgia, S recoveries, the 2 failures being in hysterical sub jects. In 3 cases of migraine, 1 cured. Succeeded in 3 cases of rheumatic pains. Failed in zona and tabetic pains. Un toward symptoms: an intense headache in 1 patient and buzzing in the ears. Spiegelberg (Miinchener med. Woch., Apr. 4, '93).
Used in about two hundred cases, the majority neuralgia. The full dose of 15 grains necessary to produce relief. Foy (Med. Press and Circular, June 13, '94).