CHRONIC AFFECTIONS.—Chronic rheu matic disorders and sciatica have been ameliorated by diaphoretic doses of pilo carpine.
In a patient who suffered from two or three attacks of rheumatism yearly. the writer used hypodermic injections of pilocarpine, using 11,, grain. which led to complete recovery within six days. Drap pier (Jour. des Sci. .M6d. de Lille, Sept. 15, '94).
The fulgurant pains of locomotor ataxia may sometimes be relieved by subcutaneous injections of pilocarpine. Mitkowski has tried pilocarpine in per sistent catarrhal jaundice with great benefit, in the hypodermic dose of '/, grain every other day for three weeks. He attributes, moreover, a diagnostic value to the procedure. If the above treatment produces no effect upon the jaundice, the presence of a malig,nant growth is to be suspected.
In laryngitis with scanty secretion J.
Solis-Cohen suggests the use of from 1 to 5 minims of the fluid extract of jabo randi to 1 ounce of water, in spray locally.
Pilocarpine is a specific for croup and all croupous diseases. Its action begins
at once. The drug can be given by the mouth, subcutaneously, or in supposi tory. The duration of the disease is notably shortened by the use of pilo carpine and the mortality reduced to nil. The daily doses advised are as follow: Up to 1 year, '/, to grain; 1 to 3 years, '/, to 1, grain; 3 to 6 years, 2/8 grain; 6 to 10 years, 1, grain; 10 to 15 years, 1 to 11, grains; adults, 114 grains to 15 grains. Sziklai (Wiener med. Woch., Nos. 32, 33, '94).
In bronchitis with asthma, in winter cough, and in hiccough jaborandi has proved of great benefit.
Patient whom obstinate, continuous hiccough had brought very low, and for whom many therapeutic measures had been employed without relief. Prompt success, however, followed the adminis tration of a decoction of jaborandi. Kiithe (Med. and Surg. Reporter, Apr. 21, 'SS).