Two eases of lupus in which the re sults were very successful. In both cases there was no bad symptom. The points to be noted are preliminary scraping, the gradual increase in the amount of the drug, and the large quantity taken, as much as 90 grains a day in one case. Seen eight months later: in one ease there was a tiny focus in the interior of the nose, and in the other there was no return whatsoever. F. G. Proudfoot (Brit. Med. Jour., Jan. 2, '97).
Leprosy. — Closely associated with lupus is leprosy, in a few cases of which thyroid gland has been tried. The re sults, though promising, do not warrant even an estimate of its value, and it is hoped that its merits will be further in vestigated.
Tried tabloids on the Trinidad Leper Asylum patients. Results not encour aging. The most powerful preparation of the drug had been pushed as far as safety would allow in leprosy. Bevan Rake (Med. Press and Circular, Jan. 2, '95).
Two cases of leprosy treated by thy roid gland; beneficial influence on both. Patients seen two years later and found apparently well and able to earn their living. The disease had not advanced. C. B. Maitland (Lancet, Oct. 31, '96).
Keloid. — Thyroid extract has caused disappearance of the hypertrophic tis sues in a case reported by J. W. White.
Case following cut in which absorbent ointments, pressure by means of plaster, and other means of local treatment hav ing been tried to no purpose, put upon thyroid extract, from 2 to 4 tablets— each tablet containing 5 grains—being given daily. All local treatment discon tinued, the sear covered with a film of collodion to prevent abrasion of irrita tion and to keep up gentle pressure. In a few weeks a perceptible change noted; in six weeks the scar had, in almost its entire extent, come down to the level of the surrounding skin and the dense base had disappeared. .1. W. White (Univ. Med. Mag., Aug., '95).
EPILEPSY.—The four cases given be low would tend to show that thyroid gland is of no value in this disorder.
Cases selected for trial those in which many congenital defects were noticeable, and in which epilepsy had been a promi nent feature of the patient's life since early infancy. The administration of thyroid not attended with very good re sults. While all seemed to be benefited for the time being, permanent improve ment doubtful. Trial subjects lost from three to ten pounds in weight. The results would not seen) to justify its continued use in epilepsy, and its further administration was not attempted. L. P. Clark (Med. Record, Oct. 24, '96).