For destroying the organisms and stim ulating the ulcers, solutions of quinine, creolin, and silver nitrate tried; the lat ter gave the best results. West (Med. Record, Sept. 23, '93).
Iodized starch internally tried in more than a hundred cases, giving a mixture of equal parts of iodized starch, oil of cinnamon, and oil of fennel, about 1 grain four times a day. At the same time irrigations with a solution of iodized starch to which are added a few drops of chloroform, tincture of iodine, and oil of cinnamon given. Kotschorowsky (Se maine -AIM., No. 62, '96).
Two 'severe cases in which 1-per-cent. solutions of creolin used, with excel lent results, in severe dysentery. A pint and a half of the solution was used night and morning. Creolin is worthy of an extended trial in dysentery. George John.ston (Treatment, June 24, '97).
Antipyrine used in a case of severe acute dysentery, by rectal injection three times a day of a solution of 75 grains dissolved in 1/2 pint of water. Sedative action of the antipyrine greatly allevi ated the patient, who gained strength and soon recovered. Ardin-Delteil (Bull. G6n. de Jan. 30, '98).
Rectal injection of permanganate of potassium in the strength of S grains to the quart effective. Half of this quantity is given at a dose, and is to re main in the bowel from half a minute to two minutes. The water is either cold or warm, according to the needs of the case. If large quantities of mucus are present, an injection of a pint of water containing 30 grains of bicarbonate of sodium is to be previously used. Gasti nel (Jour. de de Paris, Nov. 19, '99).
Methylene-blue as a parasiticide aims at the pathogenic cause; as analgesic, it reduces the hyperexeitability of the large intestine; as a cholagogue, it has a very pronounced cholagogie effect. It is administered in warm injections of a litre or of half a litre at first until the intestine becomes tolerant, containing in solution from 1 to 2 decigrammes of the drug. Two to four injections are given daily. Berthier (La Mkt. Moderne, Oct. 10, 1900).
Inflation of the rectum with carbonic acid gas acts at once by anwsthetizing, relieving the tenesmus which character izes dysentery, and stimulates the circu lation, thereby relieving inflammation.
It is a more effective means than the well-known aqueous or starchy enemata. A. Bose (N. Y. Med. Jour., July 14, 1900).
Powdered cinnamon an excellent reme dial agent in all cases ranging from ordi nary diarrhwa to severe cases of dysen tery. It may be given in teaspoonful doses mixed with a little milk to rno/d it into the shape of a bolus, and chewed night and morning. A. N. Wilkinson (Brit. Med. Jour., Feb. 10, 1900).
Ko-sant (brucea Surnatrana) is very useful in the treatment of dysentery of Cochin China. There were 799 radical cures after a period of from three to six days. Only 8 cases resisted the treat ment. Ten grains are given the first day, 12 grains the second, third, and fourth, if necessary. The active principle of the plant appears to be quassine. Mongeot (Tribune MM., June, 1900).
In amoebic dysentery the use of qui nine irrigations was introduced by Loscb, who found that solutions of 1 to 5000 destroyed the organisms. Stronger so lutions-1 to 2500, 1 to 1000, and 1 to 500—arc borne well and may be injected three or four times a day. Corrosive sub limate in solution of 1 to 500 or 1 to 3000, and nitrate of silver, 30 grains to the quart, are also beneficial, but must be used more cautiously. H. F. Harris has seen benefit result from the usc of hydrogen peroxide in some cases. The ordinary commercial hydrogen peroxide is diluted from four to eight times with water and about a quart injected twice daily. The treatment is continued for one week and then the quantity gradu ally diminished.
Fifty-four cases treated by enemata of corrosive sublimate, 1 to 5000, of which G ounces were injected three times a day; later on a solution of 1 to 3000 was in jected twice daily. The fluid was not retained usually longer than ten min utes. Cases cured in from 1 to 3 days. In no case was there any sign of systemic poisoning. Lemoine (Bull. G6n. de Th6r., Jan. 30, '90).