GASTRO-INTESTINAL DISORDERS.—Ni trate of silver has been found of great value in the treatment of gastric ulcer, especially when combined, in pill form, with extract of hyoscyamus or opium.
Pyrosis is generally relieved by 1-grain doses of the oxide, given in pill form, a half-hour before meals. In dyspepsia, with yeasty vomiting, H. C. Wood has found that the use of the nitrate inter nally has given him the best results.
In chronic gastritis and gastric catarrh, when sour eructation or vomiting occurs after meals, the nitrate in doses of V, to grain, given an hour before meals, will yield good results. Forlanini, in these cases, irrigates the stomach with a solution of silver nitrate, following it immediately by irrigation with a solution of sodium chloride.
Catarrhal jaundice has been relieved by doses of the nitrate. Bar tholow advises the use of the nitrate in nervous dyspepsia, cholera infantum, and catarrhal jaundice.
In intestinal ulceration Pepper advised the use of the nitrate in keratin-coated pills.
In ulceration of the me= or rectum and in acute and chronic dysentery, rectal or colonic injections of nitrate of silver are very valuable. If the cmcum be in volved a large bulk must be used to reach the seat of the trouble; if the rec tum is the part affected not more than 4 ounces should be used. In either case the bowel should receive injections of warm water, that the contents may be removed, and the mucous membrane cleansed and prepared for the medica ment. If cneal, use 1 drachm of silver nitrate to 3 pints of water; if rectal, use 3 grains to 4 ounces. If the latter is
chronic and very obstinate, the strength may be increased to 5 grains of the salt to 4 ounces of water. A solution of com mon table-salt should be at hand ready for use, and should be injected if the action of the silver is too severe, or to stop the action of the remedy when the desired effect is produced.
In typhoid fever Pepper highly recom mended the use of the nitrate of silver to 1/4 grain, in pill) throughout the course of the disease. He believed that it modified the severity of the disease.
The oxide of silo er has been used as an alterative in doses of 1 grain, given three or four times daily.
NEnvous DISORDERS.— Silver is claimed to be the only remedy of any use in the treatment of anterior and posterior spinal sclerosis, and it has not always yielded success; the nitrate in doses or 1 grain of the oxide may be given three or four times daily.
In epilepsy and chorea silver has been largely used, but it seems to do little good in most cases. Murray (Lancet, Sept. 21, '95), however, reports good effects and some cures from its use.
In locomotor ataxia Curci claims good results from the use of the double salt: sodium and silver hyposulphite. He gives daily from to 3 grains by mouth or from to grain hypodermically. He claims that it does not stain the skin (argyria).