GENITO - URINARY DISORDERS. — In acute cystitis the lower part of the abdo men may be painted with ichthyol, pure or in a 30-per-cent. ointment, to relieve the pain. The bladder may then be irri gated five or six times daily with a warm (S6° F.), aqueous solution (2 per cent., increasing to 5 per cent.). In chronic cystitis a warm 1-per-cent. solution may he used once daily.
Gonorrhoea is amenable to urethral in jections of a watery solution (1 to 3 per cent.) of ichthyol. Neisser states that a 1-per-cent. solution will destroy gono cocci.
Iehthyol regarded best-known remedy for genitourinary affections of blennor rhagic origin. The writer used it in 110 eases, SO of which were men affected with blennorrhagia in various stages, and 30 were women showing inflamma tion of all parts of the genital apparatus. The men were given urethral injections of an aqueous solution (1 to 4 per cent.), while tampons, soaked in IO-per-cent. glycerole of ichthyol, were introduced into the vagina of the female patients. The results were brilliant. Only 7 of the men were not cured, though im proved, the rest leaving hospital entirely recovered after a treatment of from fif teen to thirty days. The women were cured without exception. P. Colombini (Commentario Clin. delle Mal. Cut. e Genito-Urin., Nos. 5, 7, '93).
Use of ichthyol strongly advised in acute urethritis, a 2-per-cent. aqueous solution being injected from five to six times daily, gradually increasing the strength to 5 per cent. As the patient improves, the number of injections are diminished to one in the morning and one in the evening. In acute cystitis the writer applies 30-per-cent. ichthyol oint ment to allay pain, and after the acute period employs irrigation, injecting about one quart of a '1,-per-cent. aque ous solution of ichthyol twice a day for a few days and then once a day. In chronic cystitis he injects, once daily, a 1-per-cent. solution of ichthyol. Villetti (Report of Inst. of Exp. Pharm. of the Royal Univ. of Rome, '94).
In cases of primary and secondary ca tarrh of the bladder the writer washes out the viscus with to 1-per-cent. solutions of ichthyol. By this means pain was relieved, miero-organisms were destroyed, and ammoniacal fermentation prevented. Colosanti (Riforma Medica, Jan. 12, '94).
Ichthyol employed with success in the blennorrhagie urethritis of women. R. Coltman, Jr. (Uni•. Med. Jour., Mar., '94).
Iehthyol in hot solutions, for urethral use (0.5 to 2 per cent.), is very valuable in acute urethritis, especially in those cases where the mucous membrane is very sensitive. In subacute urethritis, where the lesions are circumscribed, local applications (with the aid of the endoscope) render great service. Ich thyol suppositories. in the majority of cases, cause the inflammatory symptoms to disappear in the course of a prostati tis. In chronic urethritis, with infiltra tion, ichthyol by itself is inefficacious, but associated with the mechanical treat ment, or alternating with it, it appears to be of great benefit. Administered in ternally, it does not have any beneficial effect on nephritis or pyelitis. H. Lohn stein (Therap. Monats., Apr., '94).
In viilvar pruritus of pregnant women ichthyol found valuable after other methods of treatment had failed. The strength of the ointment used was about 2 drachms to the ounce. Doisey (Jour. des Praticiens; Then Gas., Mar. 15, '99).
Iehthyol as a laxative, used in fifty women suffering from various inflamma tory affections of the genitalia, accom panied by constipation and dyspepsia. It was given in pills of 3 grains each, once, twice, or thrice a day. The con stipation was overcome without colicky pain or diarrhoea. It should be given in keratin-coated pills. Gunsburg (North western Lancet, Feb. 15, 1900).
In prostatitis the injection of a small syringeful of a 10-per-cent. solution by the rectum three or four times daily re lieves the pain and causes a marked duction in the size of the swelled gland.