GENITO - -URINARY AND VENEREAL DISEASES.—By reason of their astrin gency, copper salts are frequently em ployed in weak solution for the treat ment of gonorrhcea, leucorrhcea, cystitis, etc., and in solution or crystal as topical applications to chancres and other syphi litic sores and internally in lieu of the mercury salts. In gonorrhcea and leucor rhcea, a solution of ammonium sulphate, 15 grains to 2 or 3 ounces of fluid, is occa-sionally serviceable; again, a solu tion of the sulphate, to 10 grains to an ounce of solution of subacetate of lead, the whole diluted with 8 ounces of water, is often employed for the former malady; in leueorrhcea, 40 to 60 grains to a pint of tepid water.
For syphilitic ulcerations, the deli quesced copper nitrate is frequently the most suitable application.
From 2 to 4 grains of subaeetate of copper dissolved in an ounce of water is one of the best injections for gonor rhoea; in the latter stage of the disease its effects are particularly good. Goss ("Mat. Med., Phann., and Spec. Tberap.,"
'89).
In syphilis the sulphate of copper is superior to mercury in its effects on the lymphatic system. The cutaneous sec ondary manifestations disappear but slowly under its influence, but it pre vents the development of mucous plaques and laryngeal accidents; on account of its great activity, it is advisable to in terrupt the treatment one or two days in a week. Patients at first have a great appetite; but, if the drug be too long continued, they suffer from pros tration, vertigo, and pallor, with rapid, weak pulse. It is best administered in doses of V. grain, in pills or potion as may seem best, three times daily; sul phate of iron may be added if it seems advisable. But even this dose is dan gerous when there is syphilitic cachexia, and smaller doses should be given to begin with, gradually increasing to Vio grain as tolerance becomes established. Price (N. Y. Med. Rec., Nov. 5, '94).