In cases in which women who are usually regular pass over a period, as well as in habitual abortion, exhibition of 5 to S grains of acetanilid, repeated in one. two, or four hours as necessary, advocated. in eases of ovarian irrita tion, where there seems to be tendency to separation of ovum at what would have been a menstrual period, more or less regular use of viburnum prunifolium and potassium bromide, with aeetanilid at time of each periodic disturbance, recommended. In emergency cases ace tanilid 10 to 15 grains, repeated at short intervals, should be given. but in every instance individual susceptibility should he considered. Harnsberger (Jour. Amer. Med. Assoc., Oct. 22, '98).
Twenty-one eases of abortion and premature labor, with death of the em bryo or foetus. These were treated by prolonged rest in bed, and by the ad ministration of iodide of potassium and iron throughout the entire pregnancy. The author's cases may be divided into three classes: one, syphilitic, in which the syphilis was old or hereditary; the second class, in which the kidneys were very deficient in action and the patient was threatened with nephritis; and the third class, in which the patient was constantly absorbing necrotic material from a chronic endometritis. He be
lieves that the treatment acts by pre venting the rupture of vessels in the placenta. Stress is also laid upon the chronic ancemia present in these eases, for which the author uses iron. Lomer (Zeits. f. Geb. u. Gyniik., Bd. xlvi, II. 2, 1901).
Potassium chlorate recommended in habitual abortion. As soon as the pa tient is pregnant 3-grain doses of potas sium chlorate are given. This is con tinued during the entire period of gesta tion, decreasing the daily dose of the drug in the last weeks to grains. \o untoward effect has been observed, either on the mother or the child, from this treatment. The pregnancy was brought to normal completion in a num ber of women who previously had noth ing but miscarriages. S. Remy (Semaine Medicate, xxii. No. 39. 1902).