INFLAMMATION AND SUPPURATION.— In acute catarrhal inflammation of the air-passages 10 grains of quinine com bined with Dover's powder, opium, or morphine, if given early, will avert the attack. Ten grains of quinine given at the beginning of an attack of acute ton sillitis will sometimes abort the disease and prevent the formation of pus.
In influenza S grains of quinine taken every day or two acts efficiently as a prophylactic.
In the broncho-pneumonia of measles large doses of quinine relieve the ca tarrhal pneumonia and retard or prevent cheesy degeneration of the lung.
In the lobar pneumonia of children 2 grains of quinine given three times daily will favorably influence the disease. In the pneumonia of adults quinine checks the escape of the white blood-corpuscles and prevents the exchange of oxygen by the red blood-corpuscles. In croupous pneumonia, pleurisy, and endocarditis 20 to 40 grains of quinine, administered during the congestive stage and before exudation has occurred, is said to abort the disease.
In septicemia, pycemia, and puerperal fever good results are obtained through the use of from 5 to 20 grains of quinine every four hours. When abscesses are present quinine reduces the discharge and prevents sapramia or pyaemia. In erysipelas quinine may be given alone in doses of from 5 to 20 grains every four hours or in smaller doses (2 to 5 grains) combined with the tincture of the chlo ride of iron (10 to 20 minims).
TONIC.—As a tonic, quinine is not only a simple bitter, but it also seems to have a direct effect in increasing the number of the red blood-corpuscles. The tonic dose of quinine is from to 2 grains. In all atonic disorders—such as neu ralgia, dyspepsia, night-sweats of phthi sis, general debility, neurasthenia, etc.—
quinine is a reliable remedy. In simple debility or that following convalescence from an acute disease, quinine in 1- or 2-grain doses given three times daily will prove beneficial. Quinine is useful when prolonged mental or physical strain is to be undergone; 2 to 4 grains daily will often prevent exhaustion and sup port the system.
In hemicrania due to malarial intox ication, and associated with a nervous condition or hysteria, the valerianate of quinine in doses of from 1 to 6 grains, repeated every two to six hours, will afford relief.
Catarrh of the stomach, due to alco holic excess or not, will be benefited by small doses of quinine hydrochlorate, temporarily employed; its value is en hanced by combining it with a mineral acid; its beneficial action ceases when irritation of the gastric mucous mem brane is produced through its use.
In subacute gastro-enteritis (cholera infantum) quinine will often effect a cure after astringents and laxatives have failed. Quinine is also good in the fol lowing condition: Tenesmus, and after much-straining the patient voids a trans parent mucus streaked with blood, with no fever or other disturbance of the bowels, and stools, when passed, are natural (Bartholow).
In delirium tremens tonic doses of qui nine do good. In bronchorrhcea quinine in tonic doses will lessen the discharge. In cases of prolonged suppuration qui nine in tonic doses is of value as a sup port to the system.
In the eruptive fevers, variola, scarla tina, measles, etc., quinine in small doses, frequently repeated, are valuable in ady namic states, and in larger doses at longer intervals to control hyperpyrexia.