Gurjun-oil, obtained from the Dip terocarpus Loris, a tree growing in east ern India, has also been considerably used, with varying results. It is given internally in capsules or in emulsion with lime-water, the dose of oil varying from 1 to 3 drachms. It is especially indicated in the anmsthetic form. The same solu tion is also applied over leprous sores as a dressing. Better results have been ob tained by Phillippo, by the use of the latter externally and chaulinugra-oil in ternally.
Ichthyol has been strongly recom mended by 17nna, who gives about 10 grains a day in divided doses. soap or the pure drug may also be ployed locally. Pyrogallic acid and chrysarobin have also been recominended by Unna.
Cure of a Brazilian leper hy Unna's method. Both legs and feet were rubbed ith a 10-per-eent. pyrogallic-acid oint ment, and the rest of the body with a 10 per-cent. chrysarobin ointment, twice daily. The face was covered with a strong creasote plasterunull once a day, the jaws, however, being painted with zinc gelatin. Later, the larger tubercles were cut out and the patient given ichthyol internally. The patient re covered by the end of two or three months. Dreckmann (-Berliner klin. Woch., Apr. 29, '89).
Crocker has recently used corrosive sublimate hypodermically. A Pravaz syringeful of the solution, yarying in strength according to age, is injected into the buttock once a week. Europhen, thyroid substance, salicylic acid, and airol may also be mentioned among the remedies meriting a trial.
[Speaking of the use of mercury in lep rosy, it seems to me—judging front ex perience acquired in the treatment of tuberculosis—that tonic doses of calomel (V„ grain three times a, day) should prove advantageous. (See MERCURY, PHYSIOLOGICAL ACTION%) They dis tinctly increase the number of red blood corpuscles and stimulate nutrition. C. E. DE M. SAJOUS.] Europhen successful when given a long time every day or every other day sub cutaneously:— Europhen, 7 '/,„ grains.
Oil of sweet almonds, 2 '/, drachms.
Filtered and sterilized during twenty four hours. Goldschmidt (Revue de Then -.1116dico-Chir., Jan. 15, '95).
Two cases of leprosy treated by the thyroid-gland substance in both of which there was considerable improvement in the local lesions and general condition. C. B. Maitland (Lancet, Oct. 31, '96).
The followilm. method is recom mended:— 1. Local treatment with a 20-per-cent.
salicylic-acid salve. This is applied over the diseased spots after having been rubbed with pumice-stone.
2. Administration of large doses of oleum gynocardhc, 8/., drachms.
3. Strong mineral-baths, 45° to 53° C., from 3 to 5 baths a day for a period of abont one month. E. Baelz (Berliner klin. Woch., vol. x_xxv, Nos. 46, 47).
The therapeutic qualities of the sinu tree ( the Excorew.i agalloclea) should be investigated scientifically. This plant, when cut. exudes a thick, milk-white juice that is mildly irritating. Its action may either be to produce a reactive in flammation in the skin or to kill the lepra bacilli. L. Lewin (Dent. med. Woch., May 26, '98).
Six eases of leprosy treated by injec tions of caeodylate of soda. Injections were made daily for several weeks, as a rule. The (lose was 5 centigrammes C/12 grain). Four cases were tubercular lep rosy and two nerve leprosy. All im proved in general health and gained weight. In four eases; there was rapid healing of ulcers. The drug is not a specific against leprosy, but a useful therapeutic agent. Ilaynaud (Jour. des Mal. Cut. et Syph., Dee., 1901).
Tuberculous nodules may be destroyed by galvanocautery or tbermocautery fol lowed by local antiseptic lotions. If this procedure is objected to, their absorption may sometimes be obtained by local ap plications of iodine or mercurial oint ment. Besnier uses with success in tuberculous cases a form of treatment combining several measures.
Internal treatment (chaulmugra-oil, up to 300 drops; salol, up to 5 grammes daily) perseveringly administered. Each tubercle is cauterized interstitially by means of single or milltiple points, or by eleetroeaust:e bars when the surfaces to be destroyed are large. After cauteriza tion should follow daily spraying with weak carbolic-acid water and dressing with sublimate or iodoform gauze, to gether with the management of cieatriza tion by means of nitrate-of-silver or zine pencils. The same galvanocaustie appli cation should be made to all affected points of the mucous membranes of the lips, nose, mouth, tongue, and pharynx. By their means it is quite easy to check and destroy the leprous foci so common in all these parts, and the results ob tained are very remarkable. E. Besnier (Univ. Med. Mag.; "Pictorial Atlas of Skin Dis.," etc., Part IV, '96).