After four weeks she began to lose power in the extremities and rapidly became almost completely paralyzed. There was pain and parmsthesia in the extremities. She began to improve, although inco ordination of extremities well marked. Eight months later the patient was able to feed and dress herself and walk, but she remained an invalid a long time. A. R. Parson (Dublin Jour. of Med. Science, Sept., '95).
The radical cure of epithelioma by arsenous acid. Arsenic in powder prov ing abortive, a solution of arsenous acid in equal parts of rectified spirit and water, of the strength of 1 part of the acid to 150 of the menstruum employed. The first step is to thoroughly cleanse the sore by vigorously rubbing or scraping the raw surface, a moderate quantity of blood being allowed to flow. The surface of the ulcer is then thoroughly moistened with the solution, shaken up before using and allowed to dry, preferably without dressing of any kind. A scab forms, over which the solution is applied daily. The margins of the scab tend to separate from the subjacent tissues; the treat ment is continued until the scab is only retained in place by a few loose adhe sions. These are divided, the scab re moved, and a fresh application of the arsenical solution is made. If on the following day the resulting scab is thin, of a light-yellow color, and easily de , tachable, it indicates that the tissues no longer comprise any trace of cancerous growth. If, on the other hand, a dark colored, firm, and closely adherent scab again forms, the whole treatment must be repeated. The thicker the resulting scab, the more energetic should be the treatment: that is to say, the stronger should be the solution, the strength of which may then be increased from 1 in 150 to 1 in 100 or even to 1 in SO. When the desired result has been attained, there remains a granulating wound, cov ered with a delicate, white pellicle, to be dealt with on general principles. Czerny
and Truneck (Med. Press, May 26, '97).
Case of epithelioma, in which recur rence had taken place after surgical in terference, treated with painting the growth with Czerny's solution of arsenic, every two days. Cure took place in short time. Borde (Ann. de Derm. et de Syph., No. 2, '98).
Case of epithelioma of face treated with arsenous acid, which was applied to the surface of the ulcer and left exposed to the air, after the method of Czerny. Growth w as completely destroyed by third month, and a month subsequent to this period the ulcer had cicatrized. Czerny's method consists in using three solutions of arsenous acid in equal parts of water and ethylic alcohol. The first solution is of the strength of 1 to 150, and is applied directly to the ulcerated area. The second and third solutions are stronger and are applied to the scab. The ulcer is touched with a solution every day, and, if the pain of application is severe, hypodermic injections of mor phine are given. When the scab drops off, the raw surface is treated as is an ordinary wound. Hermet (Lancet, Mar. 26, '98).
Warts sometimes yield rapidly under the internal use of arsenic in small doses.
The internal administration of the liquor arsenicalis in the treatment of warts recommended. Report of a num ber of cases in which great success fol lowed its use, and without any external application whatever. Pullin (Bristol Medico-Ch!r. Jour., Dec., '87).
Internal use of arsenic recommended for the removal of warts on the hands. The commencing dose for children is V4 drop three times a day, the quantity being gradually increased. Paul Muller (London Lancet, July 4, '91).