OPHTHALMIC DISORDERS.—Pil0Carpille is useful in all disorders; of the eye asso ciated with increased ocular pressure. De Schsveinitz recommends very highly the hypodermic rise of pilocarpine to grain daily) for opacities of the (1/12 vitreous humor. Diaphoresis should be avoidtd. As a myotie (1 to -1 grains to tl e ounce) it is rapidly taking the place t f tst rine: 1 or drops every hour may t used until the patient is relieved. 1%itearpine is useful as a tonic to the cp.: to relieve eye-pain after excessive use of the eyes use grain of pilo t arpine and .1 g-rains of boric acid to the t.tinee of distilled water, a few drops of the solution being dropped into thc eye three times daily (Hare). Clinical re orts show that pilocarpine in small doses is a very good remedy in tobacco amblyopia and alcoholic amblyopia. Burnham, of 'Toronto, reports the good tifects of the remedy in a ease where the centre of each cornea was studded with infiltrations: the pupillary area was in volved and vision was imperfect. A few drops of a 2-g.rain solution of pilocarpine may be employed locally with advantage in rhenmatic iritis. Staderini advises pilocarpine nitrate (i/s to 1/is grain) hypodermically„ in many inflammatory diseases of the eyes, especially in those consequent upon rheumatism, as epi scleritis, iritis, and idiopathic optic neu ritis.
Good results from injections of small amonnts (2 to 3 centigrammes) of con centrated solutions of pilocarpine in cases of blood in the anterior chamber. and in vitreous opacities after iridocyelitis and choroiditis without general disease. Bock (Centralb. f. die gesammte Then, Mar., 'SS).
In the treatment of conditions of the eye and ear in which jaborandi is thought to be useful, it is probably better to ad minister the alkaloid pilocarpine hypo dermically rather than to employ the in fusion. Laval (Ther. Gaz., Sept. 15, '97).
Gratifying results obtained with pilo carpine in the treatment of interstitial keratitis. traumatic purulent iritis, vitreous opacities. and retinochoroiditis. Some nerve-specialists place great reli ance upon the drug, in toxic insanity after influenza, autointoxication, and similar processes, the brain rapidly clearing after two or three sweats. Apart from its action hypodermically, pilocarpine or the fluid extract of jaborandi in small doses by the month has been found to be of value, especially in degeneration of the vitreous. The persistent nausea so common after the use of the drug is usually relieved by small doses of chlorodyne, as suggested by Dr. H. C. Wood. H. F. Hansell (Phila. Med. Jour., May 4, 1901).