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Phies

thyroid, acromegaly, extract and atrophy

PHIES. — Muscular Atrophy.— The fact that two cases of muscular atrophy were greatly improved and reported as such by so reliable an observer as Lepine would indicate that a portion, at least, of these cases can be benefited.

Thyroid gland employed in two cases of muscular atrophy and successful re sults obtained. In one case—a man, 44 years of age, who had suffered for eight years-2 ounces daily had been admin istered for about two months. Improve ment had taken place in about two weeks after the beginning of the treat ment. The patient felt stronger and had been able to walk alone, which he had not been able to do for some time. LC pine (Revue Inter. de INI5d. et de Chin, Aug. 10, '90).

Acromegaly.—The reports of cases of this disease treated with thyroid have been insufficient to warrant a conclusion, but it would seem probable that con ditions due to disorders associated with myxcedema or goitre could alone be ex pected, the osseous hypertrophy being beyond the remedial process.

Case illustrating the association of megaly and goitre. (C. R. Murray.) Case of aeromegaly treated with dried thyroid extract in gradually increasing doses until 12 grains a_ day were taken, besides galvanism and tonics. Three months later she was feeling very much better, her memory had improved, and she spoke and moved more rapidly. She

had lost over twenty pounds in weight, but felt stronger. General condition practically the same. The history of the case and the marked physical changes leave little doubt that it was a case of acromegaly, but certain anomalous symp toms—such as the puffy conditions of the eyelids, may. however, have been simply the result of anemia, though its appearance was somewhat different ; the slow speech, and the altered mental state —suggested that her condition was also associated with a loss of function of the thyroid gland. G. G. Sears (Boston Med. and Slug. Jour., July 2, '96).

Case of a woman, 26 years old, who had suffered from acromegaly for upward of two years, and who for a period of five months had been treated with mixed pituitary and thyroid extracts, with great improvement. The superficial re semblance between acromegaly and myx (edema seemed to justify the administra tion of thyroid extract, especially as, in several cases of acromegaly, treatment with pituitary extract alone had failed to effect any improvement. Itolleston (Brit. Med. Jour., Apr. 17, .57).