Belladonna often effects a surprising reduction in the curve of at tacks, but fails after prolonged use. At the first sign of any symptoms of intoxication it is advisable to discontinue the preparation (vertigo, tickling in the throat, dilatation of the pupils). Belladonna may be used by itself [pul. radic. belladonna 0.1 Gm. (1/ gr.) or with sulphate of quinine, 0.5 Gm. (71 gr.) sacch. 2.0 Gin. (30 gr.), divided into ten powders, one powder two to three times daily; or its infusion, 0.5-1.0 to 1S0.0 (7/-15 gr. to 6 oz.), a small spoonful every two to three hours; extract of belladonna, 0.02-0.1 to 10.0 c.c. (1-11 gr. to 21 dr.) of aqu. amygdal. dulc., 10 drops every three hours, or extract belladonna 0.1 Cm. (1 gr.), sacchari 2.0 Gm. (/ dr.), divided into ten powders, 3 to 4 powders daily; also atropine, 0.005 to 100.0 c.c. gr. to 3 oz.) of water, twice daily 1 teaspoonful. A sedative action on the whooping-cough is exercised by the bromides, 1-3 Gm. (15-45 gr.) a day; bromoform, for infants 3 to 4 drops, for older children 5 to 7 drops, three to four times daily; fluoroform, a 2 to 21 per cent. aqueous solution; a coffee—small —or teaspoonful according to the age three to four times a day. Thymo bromal maceration of thyme herb, folio, ca-stanem vesc{e, radices Senegal, to which bromoform is added, 15 to 20 drops daily).
If the cause of the disease is severe and all the attempted remedies prove inefficient, we have to resort to morphine and the allied alkalies, especially when it is necessary to procure rest for the child after several sleepless nights with many paroxysms. This object may be accomplished by cautious doses of morphine itself, 0.0025-0.005 Gm. gr.) a day; or by codeine, 0.005 to 0.01 Gin. to Z. gr.); or by heroin, 0.0025 to
0.005 gr.) twice a day. A codeine preparation ( :3 per cent. codeine and 97 per cent. extract of elecampane root) has recently been warmly recommended.
The saccha-rated extract of thymus, 2 to 3 spoonfuls a day; hydro chloric phenocollum [0.5-3.0 Gin. gr.) to 90 per cent.' of a decoction of alth,Ta and 10.0 of cherry syrup, 1 dessertspoonful every two hours] and a great many other remedies are said to have a specific influence on whooping-cough.
Many observers claim to have seen successful results from certain physical curative methods, and a trial of such under certain circum-• stances can certainly be recommended. In this category belongs respi ration in compressed air (in the pneumatic cabinet). Regular adminis tration of tepid baths and carbonic acid baths, will not fail to influence favorably the general condition, if not the pertussis itself.
Within the last few years vaccination has been warmly recommended by many as a prophylactic and therapeutic agency against pertussis. It is claimed to bring about a favorable change in the course of whoop ing cough and at times to diminish the susceptibility to infection. But control experiments have proved vaccination to be inefficient.
Intubation (according to O'Dwyer) is rather too energetic a method to find many advocates. Yet it may be beneficial when the course of the whooping-cough is severe.
The treatment of the complications of whooping-cough depends upon the nature of the complicating disease. A prophylactic measure may be noted which is said to be able to prevent the development of capillary bronchitis, namely, Schultze's swinging as recommended by Raudni tz.