The attenuation was accomplished in the fob Icwing manner: If the drug was a vegetable substance, a strong tincture was made and called mother-tincture. (1f this. two drops were taken, added to 99, drfp=, of alcohol. and agitated. This v.as marked first dilution. Two drops of this with 98 drops of alcohol constituted the second dilution. the third in a similar manner. and so on. This constituted what was known as the centesimal scale. Sonic preferred adding one drop of tincture to nine drops of alcohol. the label being first decimal. second. third. etc., according to the number of attenuation desired. Insoluble substances were triturated with sugar of milk in the proportions of one grain of the drug to 99 of sugar. or 9. as the physician deemed best. \\lien the fifth trituration was reached. the substance, now claimed to be soluble. was dissolved in dis tilled water. and the further process carried on with alcohol as in the case of tinctures.
Hahnemann writes. quoting from the first American edition of Organou .11(dieini (Phila delphia, IS3(1) : "Diseases are dynamic (spiritu al) aberrations. which our spiritual existence undergoes in its mode of feeling and acting—that is to say. immaterial changes in the state of learnt" ( p. 19). "A honnropathie dose. can scarcely ever be made so small as not to amend and, indeed. perfectly p. 1571. "It will stand good as a homeopathic rule of cure. refutable by no experience whatever, that the best dose of the riehtly selected medicine is ever the sinalleAt" (p. 1s7). \\Then describing the preparation of 'potenees' of fluid dilutions, the author says: "These manipulations are to be conducted thus" (by adding . drops of a pre ceding 'potence' to PS drops of alcohol and slink ing twice) "from the first up to thethirtieth or •1, cillionth development. of power. which is the one in most general use" (p. 200). The effect of shaking. on lionneopathie medicines, "is so ener getic that bitterly 1 have been forced by experi tin, to reduce the number of shake, to two, which 1 formerly prescribed ten to each dilution" t11, 205). "The best mode of administration is to make use of small globules of sugar, the size if a musta•d-seed; one of these globules having imbibed the medicine, and being introduced into the vehicle, forms a dose containing about the three-hundredth part of a drop; for three hun dred of such globules will imbibe one drop of alcohol." "By placing one of these on the tongue, and not drinking anything after it, the dose is considerably diminished. But if the pa tient is very sensitive, and it is necessary to employ the smallest dose possible, and attain at the same time the most speedy results, it will be sufficient to let him smell once" (p. 207).
The directions for smelling a 'remedy' are as follows: "The patient should hold the phial con taining she globule under one nostril, when one momentary inhalation of the air in the phial is to be made; and if the dose is intended to be stronger, the same operation may be repeated with the other nostril" (p. 191). Hahnemann
considered mesmerism It homo•pathie remedy. He says: "This curative power, of whose efficacy none but madmen can entertain a doubt. which through the powerful will of a well-intentioned individual, influences the body of the patient by the touch, aets hon•opathieally, by exeiting symptoms analogous to those of the malady" (p. 210).
In 1813 au epidemic of typhus fever occurred ie Leipzig. during which it is Said that seventy three patients were allotted to Hahnemann for treatment. Of these it is claimed that but one died. Many of his claims were denied and many of his ideas were ridiculed. As a result of the opposition of the apotheearies' guild he was for bidden to prepare his OW11 medicines for pay. In spite of all opposition. he and his pupils con tinued their practice and gave the remedies gratuitously- ivlien they were not allowed to take pay. Finally, opposition and social ostracism so discouraged Hahnemann that he left Leipzig in 1820 for Rothen, where. under the patronage of the Doke of Anhalt. he had a certain vogue. Up to this time homoeopathy was centred in the per son and teachings of Hahnemann: but now that he was absent. his pupils, already having become doctors of medieine, began, in 1821, the publica tion of the first hotmeopathie journal. the Ar chive of the Ifornfropathie Method of Curing. This publication was continued until 18(3. The growth of homoeopathy in Germany has ever been ,low. In Austria. Immompathy was first official ly known in 1819. in which year the Emperor Francis I. decreed that the method should lie for bidden. Afterwards it was taeitly permitted. and the decree was revoked in 1837. Since 184f; there flan been no governmental interference with individual preference. Ilomo•path• was intro iineed into Russia in 1823. There, as elsewhere, it- pioneers were laymen, and its growth has been slow. It was introduced into Great Britain in 1827, by Quin, a physician. Shortly after, the medical opposition was so great as to prevent those who desired to practice it from obtaining a decree entitling them to register as physicians. At present there are no restrictions placed 11111111 any person desiring to practice this system, but there are no legally incorporated schools for in strnetion. In France, lionampathy was first sys tematically- tried in the year 1830. It steadily grow in favor until 1835, when Hahnemann, set tling in Paris, gave the cause a powerful impetus. He grouped around him a large number of able men, and until his death in 1843 Paris was the .le•ea of The laws of France, as of most countries in Europe, discriminate against honneopatliy, and no place of preferment or emolument is allowed its adherents. As a rule, homoeopathic medical colleges are not legalized in European countries.