ACRIFLAVINE, a coal tar derivative, in the form of a reddish-brown crystalline powder, possessed of antiseptic proper ties. Weak solutions are pale lemon-yellow and should be freshly made. A modification, known as neutral acriflavine, has now almost supplanted the older drug, as it is less irritant and can be used in stronger solutions. Its singular advantage over other anti septics is that it is particularly effective in the presence of serum, as in wounds. Its high cost, as compared with other local anti septics, limits its use. It is commonly employed in solutions of to g-fr as a wash or dressing in fresh wounds and infected Wounds; in cases of gonorrhoea, by instillation; and in disinfection of the skin before operation. Under certain conditions and for certain bacteria it is more effective than tincture of iodine or mercurochrome.