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CENTA), and this region is the cloaca into which the aliment ary, urinary and generative ca nals or ducts all open, but later two lateral folds appear which, by their union, divide the cloaca into a ventral and a dorsal part, the former being genito urinary and the latter alimentary or intestinal, In this way the rectum or dorsal compartment is shut off from the genitourinary. Later an ectodermal invagination at the hind end of the embryo develops and forms the anal canal; this is the proctodaeum, and for some time it is separated from the hind (caudal) end of the rectal part of the mesodaeum (or part of the intestinal canal formed from the mesoderm) by a membrane called the anal membrane. This is eventually absorbed and the digestive tract now communicates with the surface by the anus.

Comparative Anatomy.

Theprimitive condition of the ver tebrate alimentary canal may be described as a straight, simple tube, consisting of an anterior portion, formed by an ectodermal invagination, a long median portion lined by endoderm, and a short posterior portion formed by ectodermal invagination. In the lower vertebrates the primitive tube subserved also the pur pose of respiration, and traces of the double function remain in the adult structure of all vertebrates (see MOUTH, PHARYNX). In fish, the pharynx, or branchial region, suddenly becomes nar rower, posterior to the gill-slits, to form the oesophagus; in higher animals the oesophagus, in the adult, is separated from the primitive pharyngeal region and lies dorsal to it. Probably, in the primitive vertebrata, the entire alimentary canal was lined with ciliated cells. Traces of this ciliation persist in many living forms.

The oesophagus is essentially merely a passage, as straight as may be, from the pharynx to the stomach, varying in length with the length of the neck and thoracic regions in different animals, and in calibre with the nature of the food. It is almost invariably lined with a many-layered epithelium, forming a tough coating, readily repaired and not easily damaged by hard food masses. There are few exceptions to this structural and functional sim plicity. In fishes (see ICHTHYOLOGY, Anatomy) the swim-bladder is developed as a dorsal outgrowth of the oesophagus and may remain in open connection with it. In many birds part of the oesophagus may be temporarily dilated, forming a "crop," as for instance in birds of prey and humming birds. In the flamingo, many ducks, storks and the cormorant the crop is a permanent although not a highly specialized enlargement. Finally, in the vast majority of seed-eating birds, in gallinaceous birds, pigeons, sandgrouse, parrots and many Passeres, particularly the finches, the crop is a permanent globular dilatation, in which the food is retained for a considerable time, mixed with a slight mucous se cretion, and softened and partly macerated by the heat of the body. Many birds feed their young from the soft contents of the crop, and in pigeons, at the breeding season, the cells lining the crop proliferate rapidly and are discharged as a soft cheesy mass into the cavity, forming the substance known as pigeon's milk.

Stomach.—Wherethe oesophagus passes into the stomach, the lining wall of the alimentary tract changes to a mucous epithelium, consisting of a single layer of endodermal cells, frequently thrown into pits or projecting as processes; from being chiefly protective, it has become secretory and absorbing, and maintains this character nearly to the anus. The fundamental form of the stomach is a sac-like enlargement of the canal, the whole form ing an enlarged bent tube. At the distal end of the tube the in testinal tract proper begins, and the two regions are separated by a muscular constriction. In fishes the stomach may be a simple bent tube, or ari expanded, globular or elongated sac. In Batra chia and Reptilia it is in most cases a simple sac, marked off from the oesophagus only by increased calibre. In the Crocodilia, how ever, the anterior portion of the stomach is much enlarged and very highly muscular, the muscles radiating from a central tendinous area on each of the flattened sides. The cavity is lined by a hardened secretion and contains pebbles and gravel for me chanical trituration of the food, so that the resemblance to the gizzard of birds is well marked. This muscular chamber leads by a small aperture into a distal, smaller and more glandular cham ber. In birds the stomach exhibits two regions, an anterior glandu lar region, the proventriculus, the walls of which are relatively soft and contain enlarged digestive glands. The distal region (gizzard) is larger and is lined in most cases by a more or less permanent membrane which is thick and tough in birds with a muscular gizzard, very slight in the others.

In mammals, the primitive form of the stomach consists of a more or less globular or elongated expansion of the oesophageal region, forming the cardiac portion, and a forwardly curved, narrower pyloric portion, from which the duodenum arises. The whole wall is muscular, and the lining membrane is richly glandu lar. In many mammals one, two or three protrusions of the cardiac region occur, whilst in the manatee and in some rodents the cardiac region is constricted off from the pyloric portion. In the Artiodactyla the stomach is always complex, the complexity reaching a maximum in ruminating forms. In the chevrotains, which in many other respects show conditions intermediate between non-ruminant artiodactyles and true ruminants, the oesophagus opens into a wide cardiac portion, incompletely di vided into four chambers. Three of these, towards the cardiac extremity, are lined with villi and correspond to the rumen or paunch ; the fourth, which lies between the opening of the oesophagus and the pyloric portion of the stomach, is the ruminant reticulum and its wall is lined with very shallow "cells." The fourth or true pyloric chamber is an elongated sac with smooth glandular walls and is the abomasum, or rennet sac. In the camel the rumen forms an enormous globular paunch with villous walls and internally showing a trace of division into two regions. It is well marked off from the reticulum, the "cells" of which are extremely deep, forming the well-known water-cham bers. In the true ruminants, the rumen forms a capacious, villous reservoir, nearly always partly sacculated, into which the food is passed rapidly as the animal grazes. The food is subjected to a rotary movement in the paunch, and is thus repeatedly subjected to moistening with the fluids secreted by the reticulum, as it is passed over the aperture of that cavity, and is formed into a rounded bolus. The f ood bolus, when the animal is lying down after grazing, is passed into the oesophagus and reaches the mouth by antiperistaltic contractions of the oesophagus. After pro longed mastication and mixing with saliva, it is again swallowed, but is now passed into the psalterium, which, in true ruminants, is a small chamber with conspicuous longitudinal f olds. Finally it reaches the large abomasum where the last stages of gastric digestion occur.

In the Cetacea the stomach is different from that found in any other group of mammals. The oesophagus opens directly into a very large cardiac sac the distal extremity of which forms a long caecal pouch. At nearly the first third of its length this com municates by a narrow aperture with the elongated, relatively narrow pyloric portion. The latter is convoluted and constricted into a series of chambers that differ in different groups of Cetacea. In most of the Marsupialia the stomach is relatively simple; in the kangaroos, on the other hand, the stomach is divided into a relatively small, caecal cardiac portion and an enormously long sacculated and convoluted pyloric region, the general arrange ment of which closely recalls the large caecum of many mammals.

Intestinal Tract.

Itis not yet possible to discuss the general morphology of this region in vertebrates as a group, as, whilst the modifications displayed in birds and mammals have been compared and studied in detail, those in the lower groups have not yet been systematically co-ordinated.

Fishes.—Inthe Cyclostomata, Holocephali and a few Teleostei the course of the gut is practically straight from the pyloric end of the stomach to the exterior, and there is no marked differ entiation into regions. In the Dipnoi, a contracted sigmoid curve between the stomach and the dilated intestine is a simple be ginning of the complexity found in other groups. In very many of the more specialized teleosteans the gut is much convoluted, exhibiting a series of watchspring-like coils. In a number of different groups, increased surface for absorption is given, not by increase in length of the whole gut, but by the development of an internal fold known as the spiral valve. A set of organs peculiar to fish, known as the pyloric caeca, is present in num bers ranging from one to nearly 200 in the vast inajority of fish. These are outgrowths of the intestinal tract near the pyloric ex tremity of the stomach, and their function is partly glandular, partly absorbing.

In the Batrachia the course of the intestinal tract is nearly straight from the pyloric end of the stomach to the cloaca, in the case of the perennibranchiates there being no more than a few simple loops between the expanded "rectum" and the straight portion that leaves the stomach.

In fishes, batrachians and reptiles the intestinal tract is swung from the dorsal wall of the abdominal cavity by a mesentery which is incomplete on account of secondary absorption in places. There are also traces, more abundant in the lower forms, of the still more primitive ventral mesentery.

Intestinal Tract in Birds and Mammals.

The gut must be supposed to have run backwards f rom the stomach to the cloaca suspended from the dorsal wall of the body-cavity by a dorsal mesentery. This tract, in the course of phylogeny of the common ancestors of birds and mammals, became longer than the straight length between its extreme points and, con sequently, was thrown into a series of folds. The mesentery grew out with these f olds, but the presence of adjacent organs, the disturbance due to the outgrowth of the liver, and the second ary relations brought about between different portions of the gut, as the out-growing loops invaded each other's localities, dis turbed the primitive simplicity. Three definite regions of out growth, however, are to be recognized in the actual disposition of the gut in existing birds and mammals. The first of these is the duodenum. The second portion is Meckel's tract. It consists of the part generally known as the small intestines, the jejunum and ileum of human anatomy, and stretches f rom the distal end of the duodenum to the caecum or caeca. It is the chief absorb ing portion of the gut, and in nearly all birds and mammals is the longest portion. It represents, however, only a very small part of the primitive straight gut, corresponding to not more than two or three somites of the embryo. The third portion of the gut should be termed the hind-gut, and lies between the caecum or caeca and the anus, corresponding to the large intestines, colon and rectum of human anatomy. It is formed from a much larger portion of the primitive straight gut than the duodenum and Meckel's tract together, and its proximal portion, in consequence, lies very close to the origin of the duodenum.

Adaptations of the Intestinal Tract to Function.

The chief business of the gut is to provide a vascular surface to which the prepared f ood is applied so that the nutritive material may be absorbed into the system. Overlying and sometimes obscuring the morphological patterns of the gut, are many modifications correlated with the nature of the food. Thus in birds and mam mals alike there is a direct association of herbivorous habit with great relative length of gut. In fish-eating birds and mammals, the gut is very long, with a thick wall and a relatively small cali bre, whilst there is a general tendency for the regions of the gut to be slightly or not at all defined. In fruit-eating birds the gut is strikingly short, wide and simple, whilst a similar change has not taken place in frugivorous mammals. Carnivorous birds and mammals have a relatively short gut.

The Colic Caeca.

Thesepaired or single organs lie at the junction of the hind-gut with Meckel's tract and are homologous in birds and mammals although their apparent position differs in the majority of cases in the two groups. The caeca are hollow out-growths of the wall of the gut, the blind ends being directed forwards. They vary in size within very wide limits and there is no invariable connection between the nature of the food and the degree of their development. The caecal wall is in most cases highly glandular and contains masses of lymphoid tissue. In birds and in mammals this tissue may be so greatly increased as to transform the cae into a solid or nearly solid sac.

BIBLIOGRAPHY.-T.

W. Bridge, in The Cambridge Natural History Bibliography.-T. W. Bridge, in The Cambridge Natural History (vol. vii.) ; D. S. Jordan, A Guide to the Study of Fishes; R. Owen, Anatomy of Vertebrates; M. Weber, Die Siiugethiere; W. H. Flower, The Organs of Digestion in Mammalia; R. Wiedersheim, Lehrbuch der vergleichenden Anatomie der Wirbelthiere; A. Oppel, Lehrbuch der vergleichenden mikroskopischen Anatomie der Wirbelthiere; Chalmers Mitchell, "The Intestinal Tract of Birds" Transactions of the Linn. Soc. of London (vol. viii., Igo') ; and "On the Intestinal Tract of Mammals," Transactions of the Zool. Soc. of London (vol. xvii., 1905). (In the two latter memoirs a fuller list of lit. is given.) L. Testut, Traite d'anatomie humaine (1923) ; G. A. Piersol, Human Anatomy (Philadelphia, 1918 ed.) ; E. Pernkopf, "Die Entwicklung. d. Form. d. Magendarunkanales beim Menschen," Ztschr. f . d. ges. Anat. (1 92 2) ; T. W. Todd, The clip. anat. of the Gastrointestinal Tract (Man chester, 1915). (P. C. M.; X.)

birds, stomach, portion, gut and tract