HOLDEN, SIR ISAAC, BART. (1807-1897), English in ventor and manufacturer, was the son of Isaac Holden, a native of Cumberland, and was born at Hurlet, near Paisley, on May 7, 1807. His chief discoveries were his square motion wool comber and a process for making genappe yarns, a patent for which was taken out by him in conjunction with S. C. Lister (Lord Masham) in 1847. The firm of Lister and Holden, which estab lished a factory near Paris in 1848, carried on a successful busi ness, and in 18S9, when Lister retired, was succeeded by Isaac Holden and Sons, which became the largest wool-combing business in the world, employing upwards of 4,000 workpeople. In 1865 Holden entered parliament as Liberal member for Knaresborough; later he sat for the northern division of the West Riding, and for Keighley. He died at Oakworth House, near Keighley, on Aug. 13,