APALACHICOLA, a city of Florida, U.S.A.; a port of entry and the county seat of Franklin county; on the Gulf of Mexico, about 15om. S.E. of Pensacola, at the mouth of the Apalachicola river and on a bay of the same name. It is served by river and coasting steamers, and by the Apalachicola Northern railroad, which connects at Port St. Joe with Gulf and trans-Atlantic steamers, and at River Junction with the Atlantic Coast Line, the Seaboard Air Line, and the Louisville and Nashville railways. In 1925 the population was 3,003 (State census) ; in 1930, 3,15o Federal census. The bay is well protected by several islands, and before the development of railways in the Gulf States Apalachi cola was one of the principal centres of trade, ranking third among the Gulf ports in 1835. In 1925 the total commerce of the bay was 22,906 tons, valued at $2,o6o,o82. Oysters and shrimps, fish, resin and turpentine, were the principal commodities handled.