CHARLES ESTIENNE (1504 or 1505-1564), the third Son of Henri, was also a man of considerable learning. He studied medicine, took his doctor's degree at Paris, and was for a time tutor to Jean Antoine de Baif, the future poet. In 1551, when Robert Estienne left Paris for Geneva, Charles, who had re mained a Catholic, took charge of his printing establishment, and in the same year was appointed king's printer. In 1561 he be came bankrupt, and he is said to have died in a debtors' prison. His principal works are Praedium Rusticum , a collection of tracts which he had compiled from ancient writers on various branches of agriculture, and which continued to be a favorite book down to the end of the 17th century ; Dictionarium historicum ac poeticum , the first French encyclopaedia ; Thesaurus Ciceroni anus (1557), and De dissectione partium corporis human libri tres, with well-drawn woodcuts (1548) . He also published a translation of an Italian comedy, Gli Ingannati, under the title of Le Sacrifice ; republished as Les Abusez, , which had some influence on the development of French comedy ; and Paradoxes 0553), an imitation of the Paradossi of Ortensio Landi.