The reputed prophylaetic action of quinine is but a phase of its therapeutic action; it is the application of the drug to the parasite, and not an immunizing of the body against the entrance of the parasite, one has to deal with; there fore one may confidently expect that, if it will cure a malarial infection, it will prevent its development: the develop ment, though, not the introduction of the germ. Patrick .Manson (Brit. Med. Jour., Sept. 1, 1900).
The Health Depa,rtment should have all malarial cases reported; every house should be thoroughly inspected and the inmates instructed to kill all the anoph eles in the house; to provide the win dows and doors with screens; to use every precaution to isolate the patient from mosquitoes, and to cause all the standing,. water in the vicinity to be drained or heavily treated to petroleum. NV. H. Berkeley (Med. Record, .Jan. 26, 1901).
Enchinin as a prophylactic against malaria, recommended by Celli, tried in (loses varying from 4 to S grains per day, according to age, and continued some five months preceding the malaria season. Out of 42 persons dwelling in a ma-larial district treated in this manner, 5 suffered from mild fever, while of 47 unprotected 39 were attacked. Mori (Centralia f. Bakt.„Pme 10, 1901).
Experiment by the Liverpool School of Tropical Medicine for a reduction of mosquitoes in Freetown, West Africa. 'Men were hired and divided into two gangs: a small gang of six men (called the Culex gang), to collect from private houses all the broken bottles and buck ets, empty tins, old calabashes, arid sim ilar unconsidered vessels, in which mos quitoes of the genera Slegonight and Oiled'. breed; and a. larger gang (called the Anopheles gang), to drain the pools and puddles in the streets and the back yards of the houses, in which Anophcle8 breed.
On September 17th there was no dmibt that the number of mosquitoes (A nophc/cg) in the streets dealt with was reduced; the number of pots and tins removed having inade a consider able diminution in the CH/c.r, meaning
•september 2st t lie I %till 011 t 110 tieelitil`, :111,Ir toti it %%a, already I 01 find I nophrles.
r l'it-t ['yogi-es, Report of the A.:must Mosquitoes in Sierra pt.. 1901..
V•t, n to the tollom lug simple - mill suffice to prevent ina 1 N,N., idance of fatigue and excesses kind-. Judicious.. liberal diet. .1.. use of alcoholic beverages in small • .1 .ntii s. particularly in warm coun s: spi‘e. and condiments in small pi intitn s; coffee. on account of its 1. en propertic-.
2 l'he drinking-water should be boiled .11,1 filtered carefully miles, its purity unquestionable.
3. .1voidance of exposure at night, is the time the Anophe/cs usually bite. The protection of the dwelling 1,,m-e from mo-quitoes by the use of .Me wire or other screens.. The destruc tion of tho-e mosquitoes which have :rained entrance into the house. The reening of beds at 4. The de-truction of mosquitoes by tl e draining of stagnant holes, pools, drains. and other breeding-places, and the destruction of the larvm by the use f petroleum thrown on the surface of those pools which cannot be drained. In.e ounce of petroleum to fifteen square feet will destroy the larvm. and continue .o prevent their development from two .0 four weeks.
5. The isolation of the malarial pa tn nt from Anophe/es, should it exist in ne me locality.
Even without the auxiliary action of ainine the -ystern carries on a more or h siteee--ful warfare against the plas ,,,oitim of malaria. in this combat the t, .ceytes appear to play an important r,lc. Those suffering from debilitating are usually more susceptible, r, . re wont to suffer from many re , Toni, treatment is, therefore, ,r...i,•ated, and iron in some form should admini-tere 1.
si,rnetimes it mill be neeessaiT to -tin ulate the hepatic function by the se of eholagogrues. Extractum behp fructus liquidum 17 an excellent remedy for the enteric complications of malarial infection. C. C. Beling (New York Med. Jour., Dee. 7. 1002).