QUININE).
Cinchona febrifuge (see QIIINETUM, on pages 197 and 200).
Cupreine, 1 to 15 grains.
Cupreine sulphate, 1 to 15 grains. Esencia de calasaya, 4 to 12 drachms. Compound elixirs of cinchona (all kinds), 1 to 2 drachms.
lleberden's ink (aromatic iron and cin chona mixture), 1 to 2 ounces.
Homoquinine (mixture of quinine and cupreine), 1 to 15 grains.
Cinehonine and alkaloid appears as white shining prisms or nee dles, at first without much taste, but after being swallowed developing a dis tinct bitterness on tongue and palate; it is soluble in dilute acid, in alcohol 1 to 116, chloroform 1 to 163, and very slowly so in ether and water.
The benzoate is soluble in alcohol, slowly so in water, and comes in the form of small white crptals.
I The bisulphide appears in minute trisnetric prisms, soluble in water and in alcohol.
I odosulphate of cinchonine is a dark brown, odorless powder containing 50 per cent. of iodine, and, though. some times administered internally, it finds its principal use as an external application and substitute for iodoform; it is freely soluble in alcohol and chloroform; slowly soluble in water.
Nitrate of cinch° nine appears as color less prisms, soluble in water; its value is about the same as any other ordinary salt of the alkaloid.
Salicylate of el, nchonine, introduced as a remedy for rheumatism, has never equaled the expectations; it comes in white crystals, soluble in alcohol.
Cinchonine sulphate is a fair substi tute at times for other cinchona alka loids; is obtained in hard, white, lus trous crystals of very bitter taste. It is soluble in 10 parts of alcohol, about 65 parts of water, and 75 to 80 of chloro form.
The tanuate salt is of variable com position, like most tannates; it is an amorphous, yellow powder, by no means constant as to color, slowly soluble in water, and readily so in alcohol.
Cinchonidine is usually obtained from the red cinchona, and may appear either as white prisms, or a white powder, or in light, white masses, and has an intense bitter taste; is soluble in alcohol, ether, and chloroform. in dilute acids, and in water slowly.
Cinehonidine bisulphate is soluble in water and alcohol, and comes in striated prisms. Another salt of no material
value is the borate : a white powder that is soluble only in alcohol.
The dihydrobrom ate, hydrochlorate, and hydroiodate salts appear, respectively, as slightly yellowish prisms, white prisms, and yellowish-white crystals; all are soluble in water, and the hydrochlorate in alcohol and chloroform as well.
The salicylate of einchonidine appears as white colorless microscopical crystals, soluble in alcohol, very slowly so in water.
C inchonidine sulphate presents white, silky, acicular crystals that effloresce on exposure; is soluble in alcohol and hot water; slowly so in cold water.
The lannate is a yellow, amorphous powder, practically tasteless, of uncertain and variable composition.
Cinehonine tartrate, very slowly sol nble in water, rapidly so in alcohol, is a white crystal powder.
Quinetum, known also as chinetum, kinetum, and cinchona febrifuge, is a mixture of the alkaloids of red cinchona bark, devised by East Indian authorities as a better, cheaper, and safer remedy than quinine, and it seems to have met with general favor. In the United States is prepared an elixir of all the cinchona alkaloids that is rnost palatable, known as "esencia de calasaya," which is in tended for the same precise purpose. Quinetum is an amorphous, grayish white powder, containing from 50 to 70 per cent. of cinchonidine; is soluble in dilute acids and slowly so in water. Quionin purports to be much the same thing, but is more uncertain as to com position. There is also a neutral sul phate of quinetum prepared.
Quinidine, chinidine, or conchinine, has the form of colorless, lustreless prisms, and effloresces on exposure; is soluble, 1 to 20, in alcohol, 1 to 30 in ether, and 1 to 2000 in water. Both a sulphate and bisulphate are had, the former as white needles, the latter as long, colorless crystals, both being ex tremely bitter; the sulphate is soluble, 1 to 8, in alcohol, 1 to 14 in chloroform, 1 to 100 in water, while the bisnlphate is soluble (with fluorescence) in water only.