RENAL DISEASES. — In this class of affections iron should be given with prudence, especially in chronic nephritis.
In chronic albuminuria the tincture of the chloride improves the digestion and counteracts the anaemia. Many prefer Basham's mixture (liquor ferri et am monii acetatis), 2 to 4 drachms three or four times daily, on account of its di uretic action.
There is a good deal of mischief done by iron in Bright's disease. Basham's mixture in Bright's disease was never suggested for any directly curative pur pose, but simply as a remedy for the anannia which is so conspicuous a symp tom in many cases, and for this purpose it still is and always will be useful. But not every case of Bright's disease is aummic, and as iron has no specific cura tive effect it is clearly not indicated in non-anmmic eases. Nay, more, it is often harmful. It may be laid down as a rule to which there is almost no exception that iron is not indicated and should not be prescribed in cases of acute Bright' disease. On the other hand, after 1,utt s) tt s ha's e passed am,ity 10,1 tiNaltstente sets tn, iron is often st .11,1 c ass of ill \Odell iron is ntra inditated is chronic interstitial nti Tuts, 1N iS 1110re promptly !tad dangtrously harmful than in any t aer 1,rin know n of Bright's disease.
'I .te form of Bright's disease in which n is last borne is chronic parenchy n t'llS llt I Arid lIS Hilt; iS a Ilt to ice associated Nxith more or less anivinia, it 1 t‘ mites a most valuable remedy in v, outing lids symptom. F.ven here 11,0 dos.es given are usually needlessly large. The author's practice is to deter mine the proper dose by an examination of the stools, and, if these arc decidedly blackened, too miteli is being given. On do other hand, a sligltt coloration may le permitted. Basham's mixture is no more diuretic than the bull( of water m filch constitutes its. menstruurn. James Tyson (jour. Amer. Med. Assoc., July 23, '.93).
ILEMORRIIAGE.—The astringent prep arations of iron are useful in hemor rhage. in the passive hmmorrhages (pur
pura; heemorrhagie diathesis; gastric, in tes.tinal and renal luemorrhage when due to aneemia) the tincture of the chloride, taken internally, improves the tone of the vessels and the quality of the blood.
Iron-quinine chloride is exceedingly useful in eases of post-abortuni haemor rhages, in doses of 10 drops, every one or two hours. of a 10-per-cent. solution. It is likewise of value in cases of pulmonary hamorrhage, and in profuse menstrua tion, in doses of 10 drops five or six times a day. J. Kersch (Pharni. Post, Mar. I, '91).
Case of a woman, 37 years of age, suf fering. from aneurismal dilatation of the right carotid, who after an abortion and a tedious convalescence again became pregnant and went to full term without any specially untoward symptom. ln the second week after delivery she began to show decided signs of amemia. She was given tr. chloride of iron for weeks, but gained very little and the breast-milk lessened very much. After the use of ferratin, 15 grains daily, the improve !Malt it 119 ill five days, anannia disappearing and the supply of milk re turning. S. \Voile (N. Y. Med. Jour., Dee. 7, '95).
Persulphate of iron, combined with in halations of oxygen and careful hygienic regulations, most nseful in treatment of hannoglobinuria. Baccelli (Gaz. degli ()sped. e delle Clin., Feb. 15, '97).
Ferratin has had a limited, but suc cessful, trial in the New Haven Hospital. It has been used in secondary ameinias due to luemorrhage following childbirth, etc. In primary amemia it has been used very little. The results have usually been prompt and satisfactory. Hospital and Clinic Notes (Yale .Med. Jour., June, '93).
In epistaxis and chronic coryza a weak dilution of the liquor ferri subsulphate (1 drachm to S ounces of water) has been advised, to be used in spray. The same application has been used in pulmonary heemorrhage. As it stains the teeth, its use is objectionable.