THERAPEUTICS OF CORROSIVE SUB LIMATE.—Aside from its uses as an septic (see WOUNDS, volume vi) and in syphilis (see article on SYPHILIS), the useful applications of corrosive subli mate are very similar to those of calomel, but, of course, in doses commensurate with its greater strength. Here, again, the activity of mercury- as a tonic comes manifest, provided very small doses are adhered to.
There are tunnel-ow- possibilities of danger from irritation, ete., in the use of mercury and iodine preparations to gether. Injections of salieylate of mer cury, thymol-aeetate of mercury, and ()kiwi einerettin, are nut influenced by thc coincident presence of potassium iodide in the tissues. Hence, he recom mends the salts mentioned in using mer cury with iodine. F. Lesser (Deutsche med. Woollen.. Nov. 28. 1901).
In the summer diarrhcea of children and adults very small doses are especially effective, / 1, 100-grain doses being repeated every hour or two. It stimulates the in testinal tract and acts as a germicide, thus arresting putrefaction, and rids it of its contents by gentle catharsis. It has also been found valuable in dysen tery, administered in somewhat large doses. Corrosive sublimate has also been used with advantage by rectal injections in the latter disease.
For the treatment of dysentery, ene mata of bichloride of mercury success fully employed in cases where ipecaen anha had failed, and where the patients complained from the beginning of nausea and vomiting. Two hundred and two patients were treated by calomel by the mouth and enemata of biehloride of mer cury. To those who had no gastric in tolerance calomel was given in minute doses at first. For others the enemata of the mercuric salt Were as follow: Of a solution of the corrosive sublimate, 1 part to 5000, three enemata of 6 '/, ounces each were employed per day at first. Later on, only one enema of 3 to 1000 parts was administered during the day. The enemata should be given lukewarm, and for some patients a few drops of laudanum may be added to the injec tions. Lentoine (Amer. Practitioner and
News, Afar. 29, '90).
Bichloride of mercury successfully em ployed in dysentery. Solution of 1 in 6000, or 7: grain to 6 ounces of water, was given by rectal injection. Of seventy-five cases recently treated there were but three deaths, all the others being completely cured. Roudneff (Afedit. Oboz., No. 20, '93).
lIercuric bichloride has been found efficacious in the active manifestations of gonorthcea, especially in woMen, and in gonorrhccal rheumatism.
Subcutaneous injections of the bichlo ride of mercury highly recommended for the treatment of gonorrhceal rheumatism. Jullien (La Sent. Med., Alay 16, '91).
For gonorrhceal vulvitis every part should be painted every day thoroughly with a. solution of silver nitrate (20 grains to the ounce). In cases with ten der mucosm, as in blonds and very young women, every other day is sufficient To prevent extension the vagina is to be packed with iodoform gauze, previously wrung out in 1 to 5000 bichloride solu tion, and this must be renewed once in three days. The vulva should be bathed every four hours in a lysol solution. Pryor (Amer. Gyn. and Obst. Jour., Sept., '95).
Treatment of rectal gonorrlima women consists in irrigation of the rec tum twice daily, through a speculum, with a 3-per-cent. solution of boric acid, followed by mercuric chloride, 1 to S000, half a litre of each being used. The ero sions are touched with argentamine, 2 per-eent. solution. Baer (Dent med. Woch., No. 8, '96).
It has also been highly recommended for the treatment of diphtheria, '/,„„ grain being given every three hours; but antitoxin is a much more effective went and should be given thc prefer ence.
'4 inttrual administra • 1. u other than syph i ed much pri. its-ion, owing to . .0 4. salivation and othert intrcurial poisoning.
. ally bien employed,t-cti • thi.• agent is more c '10 toxic symptoms -•.b.