Therapeutics of Corrosive Sub

mercury, solution, day, sublimate, skin, applied and treatment

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• Tr' -1:SS fn. in mercury in 9 cases spin.d meningitis occurring in 1,4 i f g,rip. Only 1 case proved .. • 1 '.e d. se varied from '/,3 to 1/, o. e hiehloride according to the f t. e patient. administered hypo lite in twenty-four hours in P.,. ..71:.1 it g and later once in forty . nr=. Consalvi (La Sem. Aft=d., '• 1. 1.".. '96 .

r— (..%,= of =evere anamiia in which *J 1.- f Inc reuric chloride and qui ,re ith good results. De - 4,1z. degli Osped.. Feb. 4. '96).

i crni •ious anxtnia in which r -.zr: cl I -ride injections were used, V, 1- adn inistered daily for two • t - Under this treatment the an • carid and the patient im . 1 in • wry way. Patera (Riforma , '96..

rn. -ueet== with mercury in cere r.. sj it.al meningitis; grain of mer r: c..1 ride hypodermically at first - --I .'•.n grain every hour until there . - tr..m: gastro-intcstinal irrita ,'. t. Jour. Amer. Med. .A.ssoc., • L -a c•o.—The external uses of bi •1,.- 3. •,t. mercury, besides its applica rqPrative field, are very nu n ••.

.1/vrr.Qcs.—In the treatment .t t.., .,r or boils, it is extremely !Ind rften succeeds in arresting t; r,arly. Compresses of a 1 to 3r.r, srlutlon applied over the spot whrn the furuncle shows its first s'zris on an extremity, baths of this very valuable. The threat ened region should be kept moist with the solutions, however.

As infection takes place from the out side, the following treatment is success ful: The entire skin is cleansed by a \Vann bath with soft soap. The furuncle and the surrounding skin are washed with a 1 to 1000 solution of mercuric chloride. The boil is then covered with phenol and mercury plaster-rnull, and the patient puts on clean linen. Twice a day new plasters are applied, and if the furuncle has opened the pus is gently squeezed out and the entire region care fully disinfected with the mercuric solu tion. Van Hoorn (Monats. f. prakt., B. 19, No. 1).

onychia maligna, malignant pus tule, and anthrax these applications are also of g-reat value. The effect is en hanced by using warm solutions. It is also used with advantage in many skin disorders, including those attending in fectious fevers. In small-pox it is quite effective in the prevention of pitting.

New way to use mercury, especially the corrosive sublimate, for preventing the pitting of small-pox: A solution of the salt is to be supplied by means of an atomizer in the following manner: For the first or second day of the eruption, the face is to be washed with soap and water, rinsed with borated water, and wiped dry with absorbent cotton before using the atomizer. After the third day the washing is unnecessary; the eyes are now protected with borated 1N-adding, and the solution applied with the atom izer. In this way the skin is given a frosty appearance, and the danger of blistering by too copious a dose is avoided. The spray is to be applied chiefly to incipient pustules. Fifteen minutes after this operation of atomizing, which should not last more than a min ute, the face is to be rubbed with a pledget of wadding dipped in a glycerin solution of sublimate of the strength of drachm to the ounce, the operation to be repeated three or four times during the twenty-four hours in the first three days, twice until the sixth or seventh day, when the spray may be suspended and the glycerin painting continued until the scabs begin to drop off. Results were highly successful except in eases of con fluent small-pox; salivation never oc curred.

The spray-solution is made up as fol lows:— 3 Corrosive sublimate, 15 grains. Citric acid, 15 grains.

Alcohol, 90°, 75 minims.

Ether, q. s. to make 121/2 ounces.

This solution contains 2 per cent. by volume of sublimate. Talamon (Then Gaz., May, '90).

The bichloride of mercury is employed locally in many diseases, and is intro duced under each general heading.

ME T HYL-BLUE.—Methyl-violet or methyl-blue, an aniline dye introduced as an antiseptic by Stilling under the name of pyoklanin, is thought to be a mixture of methyl-parasanilins in various proportions. It occurs in the form of pasty, bluish-violet, odorless crystals.

Preparations and Doses.—It may be used powdered, but greatly diluted with talc or some other inert substance (0.1 to 2 per cent.), and may be molded into pencils. It is most usually employed in solution from 1-100 to 1-2000.

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