Good results follow the use of salol in all affections of the bladder and urethra. It is especially beneficial in pyelitis, cys titis, and fermentation of urine in the bladder, by reason of its antiseptic action upon the urine. Five grains every three or four hours, or 10 grains thrice daily, appear to be sufficient in these cases.
Salol has been used extensively in in testinal disorders. Intestinal indigestion and fermentation are amenable to salol alone or in combination with bismuth, chalk, etc. Diarrhoea due to decomposi tion is arrested; the summer diarrhoea of children, dependent upon indigestion and consequent fermentation, is checked by salol by reason of its antiseptic action upon the intestinal canal and its con tents. Fussell commends the following mixture in cases of cholera morbus:— Ty' Salol, 1 drachm.
Bismuth subnitrate, 2 drachms. Chalk mixture, enough to make 3 ounces.
M. Sig.: A dessertspoonful to be taken every two hours.
Good results have been reported from the use of salol in Asiatic cholera. Girode, however, has shown that salol is apt to increase the gastric disturbance which accompanies cholera, and cautions against its use in this disease and in all in which ulcerous conditions of the ali mentary tract are present.
Mild or pernicious anmmia is greatly benefited by salol when dependent upon the development of decomposition-prod ucts.
Salol and antipyrine combined have been used successfully by Labadie-La grave for the control of uterine haemor rhage. Equal parts of these two sub stances are heated together in a test tube over a lamp until a deep-brown mixture forms. As soon as it is suffi ciently cool, a film of cotton on an ap plicator is dipped into it and passed within the uterine cavity. This is re peated two or three times in succession.
The applications are painless and are not followed by unpleasant effects; a second application is seldom needed. In fun gous endometritis the applications are made after curetting, and are found to be antiseptic, hemostatic, and tend to prevent relapse.
The employment of salol as a coating for pills designed especially for enteric medication should receive mention.
Salol has been used externally as a dressing for wounds, burns, and ulcers, as an antiseptic and deodorant, similarly to iodoform, in the form of gauze, dust ing-powder (1 part to 1-3 parts of starch or French chalk), collodion (4 parts to 4 parts of ether and 30 parts of collo dion), and of 5- to 10-per-cent. alco holic solution (with 20 volumes of water for gargling in angina, pharyngitis, etc.). or dissolved in oil, balsam, or in oint ment. In ointment and dusting-powder it has been found beneficial in impetigo, eczema, and sycosis (Saalfeld), and has been used as an insufflation for the relief of ozrcna.
A mixture of salol and iodoform, on heating, becomes liquid, and remains so for fifteen or twenty minutes at the temperature of the body has been used in irregular cavities, cold abscesses, fistulas, and bone-cavities, for the pur pose of obtaining asepsis. Replier (Sem. 1\161, No. 19, '96).
Capitan claims to abort acute coryza by using an insuffiation into each nostril of the following powder:— 13 Salol, 15 grains.
Salicylic acid, 3 grains.
Tannic acid, 2 grains.
Powdered boric acid, 1 grain.
This should not be used too freely, as it is not free from caustic action; not too frequently, and not longer than a few hours at most.
Five-per-cent. alcoholic solutions with various flavoring agents are used in the preparation of dentifrices, month-washes, and other toilet preparations.