SYMPTOMS. In from three to six days after an animal has been exposed to the virus of cattle plague, or from 30 to 48 hours after being purposely inoculated, the temperature of the is raised several degrees. A delicate thermometer introduced into the vagina or rec tum, instead of marking about 101° F., indi cates 104° to 100'. Two or three days later a striking dullness is manifested, and the animal becomes indifferent to surroundings. The pfipils of the eyes are contracted, and the animal may lie in a state of vertigo or coma. Within 12 to 24 hours the milk-seeretion is diminished by one-half or two-thirds, the mucous membrane of the mouth is generally observed to be slightly reddened, and soon a granular, yellowish-white eruption, consisting thickened epithelium cells and granules, appears on the gums round the incisor teeth, and by and by on the lips and dental pad. Some hours later the same erup tion extends to the cheeks, tongue, and hard palate. Within 48 hours a crust of epithelium covers the g lips, and month, and then, wiped away or accidentally rubbed fd, leaves the abraded membrane red and vascular and ex hibiting patches of erosion. The membrane lin ing the vagina indicates very similar appea• ances; it is reddened and vascular, dotted with grayish, translucent elevations about the size of rape-seeds. covered with a whitish-yellow, usu ally sticky and oreasioually marked with patches of excoriation. The skin is dry;
there is hence a perverted development of scarf skin, and of the oleaginous secretion of the irri tated sebaceous glands. The skin is thus invest ed with yellowish scales; while on its thinner pertions—about the lips, between the thighs, and on the udder—there arc pa polar eruptions or elevations. The animal hangs its head, arches its back, the eyes are leaden and watery, and from both eyes and nose there latterly comes a dirty, slimy discharge. Appetite and rumina tion are irregular. The breathing is oppressed; expiration is prolonged and accompanied by a peculiar grunt. The pulse is small and thready, and is quickened as death approaches. The bowels, usually confined at, first, become, toward the sixth or seventh day, much relaxed : the discharges. passed, often with pain and strain ing. are profuse and liquid. offensive, acrid, pale colored, and occasionally mixed with blood. The patient loses weight and strength, totters if it attempts to walk, and prefers to lie rather than to stand. Death usually occurs within front two to seven days, and is preceded by muscular twitchings. CI peculiar, offensive smell, a cold, elannny state of body, moaning, grinding of the teeth. and rapidly increasing prostration.