COLCHICUM (also COLOCYNTH).—Ellects : An overdose, in the course of two or three hours, causes severe pains in the stomach, intestines, and kid neys, and sometimes diarrhoea, with bloody stools. There may be local areas of anesthesia ; and, usually following a severe headache, the patient collapses, with slow and weak pulse, irregular and laboured breathing, cold and clammy skin, great muscular weakness, and, filially, complete paralysis of respiration, causing death. Antidotes and Treatment : When a large (lose has been swallowed, very little can be clone for the patient ; hut, if the close has been only moderately large, there is some hope of recovery. If vomiting does not occur, one of the usual emetics (soapsuds, ipecac, mustard, etc.), should be given, or the stomach-pump used. The violent peristalsis should be checked by the administration of opium ; and this should be followed by copious draughts of strong tea or coffee, and demulcent drinks, to counteract the intestinal irrita tion. The patient should be kept warm, and hot poultices to the abdomen are of great service.
CONIUM (POISON-HEMLOCK).—Effects Soon after swallowing the drug, there is intense irritation in the mouth and (esophagus. This is followed by nausea, vomiting, dizziness, great weariness, and often profuse perspiration.
The pupils are enlarged, and sight and hearing interfered with. There is gradually increasing paralysis, interference with circulation, rapid and weak pulse, cold and pale skin, subnormal temperature. In some cases the pre dominating symptoms are maniacal delirium, followed by clonic or tetanic convulsions. Consciousness is usually not disturbed until the later stages have been reached, The alkaloid coniin is generally fatal in (loses of one to two (Imps. Antidotes and Treatment : The stomach should he immediately emptied, the body-heat maintained by external means, and some solution con taining tannin administered. A respiratory stimulant, such as strychnine, should be given, and artificial respiration resorted to if necessary. The rest of the treatment must be directed to the prevailing symptoms.
CROTON-OIL—Effects : Profuse vomiting and purging, griping pains, collapse. Antidotes and Treatment : Empty the stomach, and administer twenty-drop closes of laudanum every twenty minutes until the volent symp toms subside. Demulcent drinks (mucilage, milk, olive-oil, etc.) should be given freely, together with alcoholic stimulants or a small dose of spirit of camphor. Warm baths are also of great service.
CYTISIS.—See LABURNUM SEEDS.